牙科种植的治愈时间可以缩短

用于治疗缺失患牙的牙科钛钉种植技术有了最新进展。瑞典哥特堡大学的研究人员通过对种植体表面微层及纳米层结构的研究，提出了一种新的方法，或许可以缩短患者的治愈时间。

“增加纳米层的表面活性，并改变种植体的传导性能，可以使我们自身的人体生物力学发生改变、加速种植体的结合。这样可以降低患者的不适感，提高治疗期间的生活质量。”

牙科种植体用于缺失牙的替代已有40年的历史。Peringvar Bränemark是发现钛具有良好生物相容性且骨种植后没有排斥反应的第一人，最近荣获了欧洲发明家奖。钛的表面包绕着一层薄氧化层。正是这层氧化物的特性，对该次回答还有不清楚的地方，建议申请加入www·yake#net#cn牙齿疾病QQ交流群144*2704^84了解,决定了种植体与骨组织能良好地结合。

Healing Times For Dental Implants Could Be Cut

The technology used to replace lost teeth with titanium dental implants could be improved. By studying the surface structure of dental implants not only at micro level but also at nano level, researchers at the University of Gothenburg; Sweden, have come up with a method that could shorten the healing time for patients.

"Increasing the active surface at nano level and changing the conductivity of the implant allows us to affect the body's own biomechanics and speed up the healing of the implant," says Johanna Löberg at the University of Gothenburg's Department of Chemistry. "This would reduce the discomfort for patients and makes for a better quality of life during the healing process."

Dental implants have been used to replace lost teeth for more than 40 years now. Per-Ingvar Brånemark, who was recently awarded the prestigious European Inventor Award, was the first person to realise that titanium was very body-friendly and could be implanted into bone without being rejected. Titanium is covered with a thin layer of naturally formed oxide and it is this oxide's properties that determine how well an implant fuses with the bone.

It became clear at an early point that a rough surface was better than a smooth one, and the surface of today's implants is often characterised by different levels of roughness, from the thread to the superimposed nanostructures. Anchoring the implant in the bone exerts a mechanical influence on the bone tissue known as biomechanical stimulation, and this facilitates the formation of new bone. As the topography (roughness) of the surface is important for the formation of new bone, it is essential to be able to measure and describe the surface appearance in detail. But roughness is not the only property that affects healing.

Johanna Löberg has come up with a method that describes the implant's topography from micrometre to nanometre scale and allows theoretical estimations of anchoring in the bone by different surface topographies. The method can be used in the development of new dental implants to optimise the properties for increased bone formation and healing. She has also studied the oxide's conductivity, and the results show that a slightly higher conductivity results in a better cell response and earlier deposition of minerals that are important for bone formation.

The results are in line with animal studies and clinical trials of the commercial implant OsseoSpeed (Astra Tech AB), which show a slightly higher conductivity for the oxide and also an exchange between hydroxide and fluoride on the surface of the oxide. Surfaces with a well-defined nanostructure have a larger active area and respond quickly to the deposition of bone-forming minerals.

The project is a collaboration between the University of Gothenburg and Astra Tech AB in Mölndal, and will be further evaluated in follow-up studies.

The thesis Integrated Biomechanical, Electronic and Topographic Characterization of Titanium Dental Implants was successfully defended at the University of Gothenburg.